Production ramp-up is challenged by several hurdles such as unpredicted events to achieve targets like providing on-time service in critical situations and under budget constraints. The interrelated concepts of resilience, agility and risk management increase the ability of the system to handle the changes effectively. Therefore, in order to successfully manage production ramp-up particularly in high variety environments, resilience, risk, and agility should be considered in a holistic way. This will help address complexity and uncertainty underlying manufacturing and service operations. This paper aims to fill this gap by reviewing the literature and reporting on the basic concepts and interrelationships of resilience, agility, and risk management in the ramp-up phase. Ultimately, the paper aims to lay some foundations for further research in the crossing of these areas.